Collagen Stimulation & Biostimulation

Liquid Facelift in Mersin

Rejuvenate your face from within using PLLA, CaHA and other biostimulator collagen-stimulating treatments. A non-surgical, natural and long-lasting lifting effect in Mersin with Dr. Doğan Uysal.

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What is a Liquid Facelift?

Liquid facelift is the general term for collagen-stimulating (biostimulator) treatments that aim to restore facial volume and firmness without surgical intervention. PLLA (poly-L-lactic acid) and CaHA (calcium hydroxylapatite) are the most widely used products in this category.

Its key difference from hyaluronic acid dermal filler is this: liquid facelift products do not add instant volume but trigger the body's own collagen production. As a result, the effect develops more slowly and gradually, yet appears more natural and lasts longer.

PLLA Treatment

PLLA (poly-L-lactic acid) is injected beneath the skin as micro-particles. Over the course of several weeks it gradually increases collagen production. 2–3 sessions, spaced 4–6 weeks apart, are typically recommended; the effect varies between individuals but can last about 18–24 months. It is one of the approaches considered for restoring facial volume, filling the cheeks, and addressing the appearance of skin laxity.

CaHA Treatment

Products based on calcium hydroxylapatite (CaHA) provide both immediate volume and long-term collagen stimulation. They are frequently chosen to define the jawline, for hand rejuvenation, and to firm the neck and décolletage. The effect generally lasts between 12 and 18 months.

Who is it suitable for?

▸People with facial volume loss and sagging
▸Those who prefer a natural, gradual rejuvenation and want to avoid a very "full" look
▸People who consider a surgical facelift but wish to avoid surgery
▸Individuals aged roughly 35–65 with noticeable skin laxity
▸Those seeking firming of the neck and décolletage

Possible side effects after a Liquid Facelift

The following effects may occur with collagen-stimulating treatments:

▸Common and temporary: redness, swelling, tenderness and bruising at the injection site
▸A localised feeling of fullness in the first few days; post-treatment massage instructions are explained by the physician
▸Less common: small palpable nodules under the skin, asymmetry
▸Rare: infection, prolonged oedema, and serious events linked to vascular occlusion

If you notice any symptom that is unusual, severe or persistent, please contact the clinic; a follow-up appointment will be scheduled.

The treatments on this page are performed at the clinic in Mezitli/Mersin by medical doctor Dr. Doğan Uysal. A consultation is carried out before treatment; suitability, potential risks and the plan are determined individually. Results vary from person to person. Any treatment plan is subject to physician assessment. To book, please use the contact page.

Last reviewed: 18 September 2026

Frequently Asked Questions

How does a liquid facelift work?

PLLA- or CaHA-based injections are placed under the skin to stimulate the body's own collagen production. Volume and firmness build up gradually over weeks and months, producing a more natural and longer-lasting result.

What is the difference between PLLA and CaHA?

PLLA is a biostimulator that gradually stimulates collagen; the effect builds cumulatively over 2–3 sessions. CaHA provides both immediate volume and long-term collagen stimulation. Which product is used is decided during the consultation.

How many sessions are needed?

PLLA typically requires 2–3 sessions spaced 4–6 weeks apart. CaHA usually produces sufficient effect in a single session. The session plan is set according to the person's age, skin condition and expectations.

How is a liquid facelift different from dermal filler?

Hyaluronic acid filler adds instant volume and is an absorbable material. A liquid facelift (PLLA/CaHA) triggers the body's own collagen production; the effect develops more slowly and, depending on the product, can last about 12–24 months.

What is the difference between PLLA and CaHA?

PLLA (poly-L-lactic acid) is a biostimulator that gradually stimulates collagen; the effect builds cumulatively over 2–3 sessions. CaHA (calcium hydroxylapatite) provides both immediate volume and long-term collagen stimulation. Which product is used is decided during the consultation.

Where is a liquid facelift performed in Mersin?

In Mersin, the liquid facelift (PLLA/CaHA biostimulator) is offered at Dr. Doğan Uysal's clinic in Mezitli, either as a single session or as part of a combined protocol.

How is a liquid facelift different from surgery?

A liquid facelift is non-surgical: no incisions, no general anaesthesia and no downtime. Topical anaesthetic cream is used and normal daily activity can be resumed the same day. Results become visible within 2–3 months and can persist for up to two years.

Who is a liquid facelift not suitable for?

It is not performed during pregnancy or breastfeeding, or in the presence of active skin infection. In cases of pronounced sagging, surgical facelift may be more effective; a physician assessment is required.